Lähteitä jotka viittaavat suramiiniin ja tai mäntyyn toimivina lääkkeinä:

Tässä on vain osa lähteistä eikä niitä ole kerätty järjestelmällisesti vaan vain esimerkeiksi. Alhaalla hakulinkki jolla voit hakea lisää!

Korona/Covid:
• Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin
• Suramin inhibits SARS-CoV-2 infection in cell culture by interfering with early steps of the replication cycle

Andioksidantti:
• Antioxidant activity and analysis of proanthocyanidins from pine (Pinus densiflora) needles
• Antioxidant Potential of Pine Needles: A Systematic Study on the Essential Oils and Extracts of 46 Species of the Genus Pinus
• Antioxidant and antiapoptotic effects of pine needle powder ingestion and endurance training in high cholesterol-fed rats
• Antioxidant principles from the needles of red pine, Pinus densi flora
• Effect of extracts from pine needle against oxidative DNA damage and apoptosis induced by hydroxyl radical via antioxidant activity
• Antioxidant, Antimutagenic, and Antitumor Effects of Pine Needles ( Pinus densiflora )
• Antioxidant Potential of Pine Needles: A Systematic Study on the Essential Oils and Extracts of 46 Species of the Genus Pinus
• Antioxidant activity and analysis of proanthocyanidins from pine (Pinus densiflora) needles
• Effect of extracts from pine needle against oxidative DNA damage and apoptosis induced by hydroxyl radical via antioxidant activity

Mikrobilääke:
• A Novel Antimicrobial Peptides From Pine Needles of Pinus densiflora Sieb. et Zucc. Against Foodborne Bacteria
• Antibacterial activity of water-soluble extract from pine needles of Cedrus deodara
• Volatile components and antibacterial effects of pine needle (Pinus densiflora S. and Z.) extracts
• Antibacterial activity of organic acids in aqueous extracts from pine needles (Pinus massoniana Lamb.)
• Antibacterial activity of water-soluble extract from pine needles of Cedrus deodara
• Antimicrobial effectiveness of pine needle extract on foodborne illness bacteria

Viruksia torjuva:

• Suramin Antiviral Therapy in the Acquired Immunodeficiency Syndrome
• Anti-viral activity of suramin against influenza A virus in A549 cells
• Suramin inhibitsin vitro infection by duck hepatitis B virus, rous sarcoma virus, and hepatitis delta virus
• Repurposing Drugs for Mayaro Virus: Identification of EIDD-1931, Favipiravir and Suramin as Mayaro Virus Inhibitors
• Suramin is a potent inhibitor of Chikungunya and Ebola virus cell entry
• Delivery of Suramin as an Antiviral Agent through Liposomal Systems
• Suramin Inhibits Chikungunya Virus Replication by Interacting with Virions and Blocking the Early Steps of Infection

Verenpainetta alentava:

• Bioactivity-Guided Fractionation of Pine Needle Reveals Catechin as an Anti-hypertension Agent via Inhibiting Angiotensin-Converting Enzyme
• Characterization of Vasorelaxant Principles from the Needles of Pinus morrisonicola Hayata

Tulehdusta lieventävä:

• Phytochemical composition, anti-inflammatory activity and cytotoxic effects of essential oils from three Pinus spp
• Bioactivity-Guided Fractionation of Pine Needle Reveals Catechin as an Anti-hypertension Agent via Inhibiting Angiotensin-Converting Enzyme
• Protective effect of pine (Pinus morrisonicola Hay.) needle on LDL oxidation and its anti-inflammatory action by modulation of iNOS and COX-2 expression in LPS-stimulated RAW 264.7 macrophages
• Anti-Inflammatory Principles from the Needles of Pinus taiwanensis Hayata and In Silico Studies of Their Potential Anti-Aging Effects
• Anti-inflammatory properties of fermented pine (Pinus morrisonicola Hay.) needle on lipopolysaccharide-induced inflammation in RAW 264.7 macrophage cells

Syöpä:

• Antioxidant, antimutagenic, and antitumor effects of pine needles (Pinus densiflora)
• Anti-oxidant activity and effect of Pinus morrisonicola Hay. on the survival of leukemia cell line U937
• Pine (Pinus morrisonicola Hayata) needle extracts sensitize GBM8901 human glioblastoma cells to temozolomide by downregulating autophagy and O(6)-methylguanine-DNA methyltransferase expression
• Anti-tumor effect of α-pinene on human hepatoma cell lines through inducing G2/M cell cycle arrest
• Inhibitory effects of α-pinene on hepatoma carcinoma cell proliferation
• A pilot study of suramin in the treatment of progressive refractory follicular lymphomas"

HIV/AIDS:

• Suramin in the treatment of AIDS: mechanism of action
• 1984—Discovery of the First Anti-HIV Drug, Suramin
• The anti-parasitic drug suramin potently inhibits formation of seminal amyloid fibrils and their interaction with HIV-1
• Suramin inhibits binding of the V3 region of HIV-1 envelope glycoprotein gp120 to galactosylceramide, the receptor for HIV-1 gp120 on human colon epithelial cells.

Autismi:

• Suramin and Autism
• Low‐dose suramin in autism spectrum disorder: a small, phase I/II, randomized clinical trial

Turvallisuus:
• As suramin is a charged molecule and does not cross the blood brain barrier it exerts neurotoxic effects in the peripheral nervous system

Muuta:
• Suramin is on the World Health Organization's List of Essential Medicines.

Hae itse lisää: Google haku

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